Is multidetector CT-based bone mineral density and quantitative bone microstructure assessment at the spine still feasible using ultra-low tube current and sparse sampling?

@inproceedings{Mei2017IsMC,
  title={Is multidetector CT-based bone mineral density and quantitative bone microstructure assessment at the spine still feasible using ultra-low tube current and sparse sampling?},
  author={Kai Mei and Felix K. Kopp and Rolf Bippus and Thomas K{\"o}hler and Benedikt J Schwaiger and Alexandra S Gersing and Andreas Fehringer and Andreas P Sauter and Daniela Muenzel and Franz Pfeiffer and Ernst J. Rummeny and Jan S. Kirschke and Peter B. No{\"e}l and Thomas Baum},
  booktitle={European Radiology},
  year={2017}
}
Osteoporosis diagnosis using multidetector CT (MDCT) is limited to relatively high radiation exposure. We investigated the effect of simulated ultra-low-dose protocols on in-vivo bone mineral density (BMD) and quantitative trabecular bone assessment. Institutional review board approval was obtained. Twelve subjects with osteoporotic vertebral fractures and 12 age- and gender-matched controls undergoing routine thoracic and abdominal MDCT were included (average effective dose: 10 mSv). Ultra-low… CONTINUE READING
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