Is monoamine oxydase-B a modifying gene and phenylethylamine a harmful compound in phenylketonuria?


We report here very high urinary phenylethylamine level in a phenylketonuric newborn and variable phenylethylamine levels in phenylketonuric patients with similar phenylalanine levels. As phenylethylamine, a very toxic metabolite of phenylalanine, is rapidly degraded by monoamine oxydase type B, an enzyme that has a very low activity in neonates, these… (More)


  • Presentations referencing similar topics