Is migraine a neuropathic pain syndrome?

  title={Is migraine a neuropathic pain syndrome?},
  author={David M. Biondi},
  journal={Current pain and headache reports},
  volume={10 3},
The understanding of migraine pathophysiology has evolved from the belief that migraine is a vascular disorder, to evidence that better defines migraine as a neurogenic disorder associated with secondary changes in brain perfusion. There is evidence to suggest that the early phase of migraine pain results from neurogenic inflammation affecting cranial blood vessels and dura. Allodynia, hyperalgesia, and expansion of nociceptive fields occur during most well-established migraine attacks. These… CONTINUE READING


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