Is long-term humoral immunity in the mucosa provided by long-lived plasma cells? A question still open.

The biology of antibody-secreting cells is still a matter of controversial discussion. One of the key questions is how the migration and lifespan of antibody-secreting cells is linked to their generation. A paper in this issue of the European Journal of Immunology provides further information on the generation of long-term mucosal immune responses; however… CONTINUE READING