Is laryngeal preservation (LP) with induction chemotherapy (ICT) safe in the treatment of hypopharyngeal SCC? Final results of the phase III EORTC 24891 trial.

Abstract

5531 Background: In 1986, the EORTC HNCCG initiated a randomized phase III trial to assess whether LP using ICT followed by radiation therapy (XRT) was as safe as the conventional treatment: total laryngectomy with partial pharyngectomy (TLP), radical neck dissection (RND) and postop XRT. Preliminary results were published in 1996; this updated analysis has… (More)

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@article{Lefebvre2004IsLP, title={Is laryngeal preservation (LP) with induction chemotherapy (ICT) safe in the treatment of hypopharyngeal SCC? Final results of the phase III EORTC 24891 trial.}, author={Jean Louis Lefebvre and D. Chevalier and Bernard Luboinski and Laurent Traissac and Guy Andry and Dominique de Raucourt and Laurence Collette and Jacques Bernier}, journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology}, year={2004}, volume={22 14_suppl}, pages={5531} }