Is it possible to identify exacerbations of mild to moderate COPD that do not require antibiotic treatment?

@article{Miravitlles2013IsIP,
  title={Is it possible to identify exacerbations of mild to moderate COPD that do not require antibiotic treatment?},
  author={Marc Miravitlles and Ana Moragas and Silvia Hern{\'a}ndez and Carolina Bayona and Carl Llor},
  journal={Chest},
  year={2013},
  volume={144 5},
  pages={1571-1577}
}
BACKGROUND Anthonisen criteria are widely used to guide the use of antibiotics in exacerbations of COPD. We evaluated the best predictors of outcomes in exacerbations of mild to moderate COPD not treated with antibiotics. METHODS We used data from 152 patients of the placebo arm of a randomized trial of amoxicillin/clavulanate for exacerbations of mild to moderate COPD. Clinical response in relation to Anthonisen criteria and point-of-care serum C-reactive protein (CRP) tests (cutoff, 40 mg/L… CONTINUE READING
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