Is intravenous administration of branched chain amino acids effective in the treatment of hepatic encephalopathy? A multicenter study.

@article{Wahren1983IsIA,
  title={Is intravenous administration of branched chain amino acids effective in the treatment of hepatic encephalopathy? A multicenter study.},
  author={John Wahren and Jacques Denis and Philippe Desurmont and L. Siw Eriksson and J M Escoffier and A P Gauthier and Lars Hagenfeldt and Henri Michel and Pierre Opolon and Jean Claude Dutailly Paris and Michel Veyrac},
  journal={Hepatology},
  year={1983},
  volume={3 4},
  pages={475-80}
}
The influence of intravenous infusion of branched-chain amino acids (BCAAs) on brain function in patients with liver cirrhosis and acute hepatic encephalopathy was examined using a double-blind, randomized study design. Five medical centers in France and Sweden participated, and 50 patients were studied. The patients received either BCAAs (40 gm per day) in 5% glucose or 5% glucose alone (placebo) for 5 days or until "wake up". Nutritional support was provided with equal proportions of… CONTINUE READING

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Current Management of Hepatic Encephalopathy

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