Is impaired set-shifting an endophenotype of anorexia nervosa?

  title={Is impaired set-shifting an endophenotype of anorexia nervosa?},
  author={J. Ray Holliday and Kate Tchanturia and Sabine Landau and David Collier and Janet Treasure},
  journal={The American journal of psychiatry},
  volume={162 12},
OBJECTIVE Set-shifting difficulties have been reported in subjects with anorexia nervosa and appear to persist after recovery; therefore, they may be endophenotypic traits. The goals of this study were to investigate whether set-shifting difficulties are familial by examining discordant sister-pairs in comparison with healthy unrelated women and to replicate, with a broader battery, the lack of influence of an acute illness state on neuropsychological performance. METHOD Forty-seven pairs of… CONTINUE READING
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