Is hammerhead self-cleavage involved in the replication of a virusoid in vivo?

Abstract

The hammerhead self-cleavage reaction is generally considered to be involved in the in vivo production of (+) and (-) monomeric RNAs of the viroid-like, satellite RNA or virusoid of lucerne transient streak virus (vLTSV) from multimeric replicative intermediates, as part of the symmetrical rolling circle mechanism. To test this, three cDNA clones of vLTSV… (More)

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@article{Sheldon1993IsHS, title={Is hammerhead self-cleavage involved in the replication of a virusoid in vivo?}, author={Colin Sheldon and R. H. Symons}, journal={Virology}, year={1993}, volume={194 2}, pages={463-74} }