Is gold necessary in so called chrysotherapy?

  title={Is gold necessary in so called chrysotherapy?},
  author={E. Munthe and E. Jellum},
  journal={Scandinavian journal of rheumatology. Supplement},
  • E. Munthe, E. Jellum
  • Published 1983
  • Medicine
  • Scandinavian journal of rheumatology. Supplement
It is postulated that the efficacy of sodium aurothiomalate and d-penicillamine could be partly dependent on the activity of sulphydryl groups. Free thiomalate, the thiol from sodium aurothiomalate was shown to be liberated in vivo and has been detected in the blood and urine of sodium aurothiomalate-treated patients. An increase in intracellular glutathione levels in response to treatment with sodium aurothiomalate and penicillamine was demonstrated and considered to be related to these drugs… Expand
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