Is ginger beneficial for nausea and vomiting? An update of the literature

  title={Is ginger beneficial for nausea and vomiting? An update of the literature},
  author={Wolfgang Marx and Nicole K Kiss and Liz Isenring},
  journal={Current Opinion in Supportive and Palliative Care},
Purpose of reviewNausea and vomiting can pose a significant burden to patients in a variety of clinical settings. Previous evidence suggests that ginger may be an effective treatment for these symptoms; however, current evidence has been mixed. This article discusses recent clinical trials that have investigated ginger as a treatment for multiple types of nausea and vomiting. In addition, the potential mechanisms of action of ginger will be discussed. Recent findingsThis article identified nine… 
Benefits of ginger in the control of chemotherapy-induced nausea and vomiting.
This complementary therapy has low cost and easy access, but no statistical confirmation of its effectiveness in the management of nausea and vomiting in cancer patients was found.
Ginger in gastrointestinal disorders: A systematic review of clinical trials
The data indicate that divided lower daily dosage of 1500 mg ginger is beneficial for nausea relief, and more extensive and well‐controlled human studies of ginger or its standard extracts are required to demonstrate its efficacy as a gastroprotective agent.
Effectiveness of Ginger in Treating Nausea and Vomiting of Pregnancy
Nausea and vomiting in pregnancy (NVP) is one of the common main complaint in pregnancy and management of NVP is included maintaining hydration, nutrition, and lifestyle modification.
Effects of Complementary Medicine on Nausea and Vomiting in Pregnancy: A Systematic Review
According to the results of this review, the majority of methods employed were effective in reducing the incidence of NVP, among which ginger and P6 acupressure can be recommended with more reliability.
The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial
This trial suggests adjuvant ginger supplementation is associated with better chemotherapy-induced nausea-related quality of life and less cancer-related fatigue, with no difference in adverse effects compared to placebo.
Effect of oral ginger on prevention of nausea and vomiting after laparoscopic cholecystectomy: a double-blind, randomized, placebo-controlled trial
This study demonstrated that 500mg oral ginger one hour before surgery in women who were undergoing laparoscopic cholecystectomy is effective in decreasing severity of PONV.
The Effect of Inhalation of Ginger Extract on Postoperative Nausea, Retching and Vomiting after Laparoscopic Cholecystectomy: A Randomized Clinical Trial
Inhalation aromatherapy with ginger extract can be used to reduce the postoperative nausea severity and the frequency of retching and vomiting in laparoscopic cholecystectomy.
Supplemental prophylactic intervention for chemotherapy-induced nausea and emesis (SPICE) trial: Protocol for a multicentre double-blind placebo-controlled randomised trial.
  • W. Marx, A. McCarthy, E. Isenring
  • Medicine, Psychology
    Nutrition & dietetics: the journal of the Dietitians Association of Australia
  • 2018
The SPICE trial is designed to meet research gaps and could provide evidence to recommend specific dosing regimens as an adjuvant for chemotherapy-induced nausea and vomiting prevention and management.
Add-On Complementary Medicine in Cancer Care: Evidence in Literature and Experiences of Integration
The integration of evidence-based complementary treatments allows for an effective response to the demand coming from cancer patients and combines safety and equity of access in public health systems.
Rapid Review of Breast Cancer Treatment Side Effects and Dietary Supplement/Integrative Options from A to Z: What Helps, Harms, or Does Nothing?
This chapter is not intended to provide a summary or exhaustive list of the conventional prescription treatment options for these side effects from A to Z because it would not only create an unreadable voluminous text, but would not serve the purpose of this text.


Ginger—Mechanism of action in chemotherapy-induced nausea and vomiting: A review
Ginger possesses multiple properties that could be beneficial in reducing CINV, including 5-HT3, substance P, and acetylcholine receptor antagonism; antiinflammatory properties; and modulation of cellular redox signaling, vasopressin release, gastrointestinal motility, and gastric emptying rate.
Ginger (Zingiber officinale) and chemotherapy-induced nausea and vomiting: a systematic literature review.
Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect of cytotoxic treatment. It continues to affect a significant proportion of patients despite the widespread use of antiemetic
Ginger in the Prevention of Nausea and Vomiting: A Review
Various preclinical and clinical studies have shown ginger to possess antiemetic effects against different emetogenic stimuli, however, conflicting reports especially in the prevention of chemotherapy-induced nausea and vomiting and motion sickness prevent us from drawing any firm conclusion.
Effects of Ginger for Nausea and Vomiting in Early Pregnancy: A Meta-Analysis
Despite the widespread use of ginger in the diet, its clinic value and safety profile in treating NVEP is still unknown, and a meta-analysis suggests that ginger is an effective nonpharmacological treatment for NVEp.
Ginger as an antiemetic modality for chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis.
Current evidence does not support the use of ginger for the control of chemotherapy-induced nausea and vomiting in CINV, and the need for more methodologically rigorous studies in this area is supported.
Effect of Herbal Therapy to Intensity Chemotherapy-Induced Nausea and Vomiting in Cancer Patients.
Findings of the study indicated that subjects receiving ginger showed significant reduction in frequency and intensity of nausea and vomiting compared to placebo receiving subjects.
Ginger for prevention of antiretroviral-induced nausea and vomiting: a randomized clinical trial
Ginger was effective in ameliorating of antiretroviral-induced N/V and frequency of mild, moderate and severe nausea were significantly lower in the ginger than placebo group.
A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting
Based on evidence from this SR, ginger could be considered a harmless and possibly effective alternative option for women suffering from NVP and pose a risk for side-effects or adverse events during pregnancy.
Evaluation of Oral Ginger Efficacy against Postoperative Nausea and Vomiting: A Randomized, Double - Blinded Clinical Trial
Use of ginger was effective at decreasing postoperative nausea and could be used as a safe antiemetic drug at post operation.