Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways?

@inproceedings{Sommer2016IsGO,
  title={Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways?},
  author={Lea M Sommer and Rasmus Lykke Marvig and Adela M. Luj{\'a}n and Anna Koza and Tacjana Pressler and S{\o}ren Molin and Helle Krogh Johansen},
  booktitle={BMC Genomics},
  year={2016}
}
BackgroundThe primary cause of morbidity and mortality in cystic fibrosis (CF) patients is lung infection by Pseudomonas aeruginosa. Therefore much work has been done to understand the adaptation and evolution of P. aeruginosa in the CF lung. However, many of these studies have focused on longitudinally collected single isolates, and only few have included cross-sectional analyses of entire P. aeruginosa populations in sputum samples. To date only few studies have used the approach of… CONTINUE READING
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