Is function of the Drosophila homeotic gene Ultrabithorax canalized?

  title={Is function of the Drosophila homeotic gene Ultrabithorax canalized?},
  author={Greg Gibson and Sven H. van Helden},
  volume={147 3},
Genetic variation affecting the expressivity of an amorphic allele of the homeotic gene Ultrabithorax, (Ubx1) was characterized after 11 generations of introgression into 29 different isofemale lines. Heterozygotes display a range of haploinsufficient phenotypes, from overlap with wild-type halteres to dramatic transformations such as a 50% increase in area and the presence of over 20 bristles on the anterior margin of each haltere. In both the wild-type and mutant genetic backgrounds, there is… CONTINUE READING

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