Is extravasation a Fas-regulated process?

  title={Is extravasation a Fas-regulated process?},
  author={Kenneth Walsh and Masataka Sata},
  journal={Molecular medicine today},
  volume={5 2},
The monolayer of endothelial cells that coats the luminal surface of the vessel wall has numerous physiological functions, including the prevention of coagulation, control of vascular permeability, maintenance of vascular tone and regulation of leukocyte extravasation. Recently, we detected functional Fas ligand (FasL) expression on the endothelial lining of blood vessels. FasL induces apoptotic cell death in the multitude of cell types that express its receptor, Fas. Here, we review the… CONTINUE READING