Is exon 5 of the PTEN/MMAC1 gene a prognostic marker in anaplastic glioma?

@article{Rustia2001IsE5,
  title={Is exon 5 of the PTEN/MMAC1 gene a prognostic marker in anaplastic glioma?},
  author={A. Rustia and Venceslao Wierzbicki and Luigi Marrocco and A. Tossini and Carlo Zamponi and Florigio Lista},
  journal={Neurosurgical Review},
  year={2001},
  volume={24},
  pages={97-102}
}
Chromosome 10 deletions are among the most common genetic changes in highly malignant glial tumors. It has been noted that loss of heterozygosity (LOH) at 10q23 is a frequent alteration in a variety of human tumors and occurs in approximately 70% of all glioblastomas. By mapping of homozygous deletions on 10q23, a candidate tumor suppressor gene has been… CONTINUE READING