Is celiac disease an autoimmune disorder?

  title={Is celiac disease an autoimmune disorder?},
  author={Ludvig M. Sollid and Bana Jabri},
  journal={Current opinion in immunology},
  volume={17 6},
Celiac disease, which results from an immune reaction to ingested cereal gluten proteins, has several autoimmune features. In particular, celiac disease patients produce highly disease specific IgA and IgG autoantibodies to tissue transglutaminase when they are on a gluten-containing diet, and they have small intestinal intraepithelial lymphocytes which can mediate direct cytotoxicity of enterocytes expressing MIC molecules in an antigen non-specific manner. Similar to typical autoimmune… CONTINUE READING
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