Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?

@article{Schuller2009IsCT,
  title={Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?},
  author={Hildegard M. Schuller},
  journal={Nature Reviews Cancer},
  year={2009},
  volume={9},
  pages={195-205}
}
Nicotinic acetylcholine receptors (nAChRs) are the central regulators of stimulatory and inhibitory neurotransmitters that control the synthesis and release of growth, angiogenic and neurotrophic factors in cancer cells, the cancer microenvironment and distant organs. Data discussed in this Review suggests that smoking and possibly other environmental and lifestyle factors increase the function of nAChRs that stimulate cancer cells and reduce the function of nAChRs that inhibit cancer cells… CONTINUE READING
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