Is bronchial hyperresponsiveness more frequent in women than in men? A population-based study.

@article{Leynaert1997IsBH,
  title={Is bronchial hyperresponsiveness more frequent in women than in men? A population-based study.},
  author={B{\'e}n{\'e}dicte Leynaert and Jean Bousquet and Charles Henry and R Liard and Françoise Neukirch},
  journal={American journal of respiratory and critical care medicine},
  year={1997},
  volume={156 5},
  pages={1413-20}
}
To test the hypothesis that a greater proportion of women than men react to methacholine challenge and investigate the possible reasons for any differences observed, we recruited 495 subjects 20 to 44 yr of age (50.9% male) in Paris and 304 subjects (51.3% male) in Montpellier (France), as part of the European Community Respiratory Health Survey. The proportion of responders (PD20 < or = 4 mg methacholine) was 33.7% in women and 11.9% in men (odds ratio = 3.8; 95% confidence interval = 2.4-6.0… CONTINUE READING
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