Is bowel preparation before colonoscopy a risky business for the kidney?

@article{Lien2008IsBP,
  title={Is bowel preparation before colonoscopy a risky business for the kidney?},
  author={Yeong-Hau H Lien},
  journal={Nature Clinical Practice Nephrology},
  year={2008},
  volume={4},
  pages={606-614}
}
  • Y. Lien
  • Published 16 September 2008
  • Medicine
  • Nature Clinical Practice Nephrology
Acute phosphate nephropathy after bowel preparation with oral sodium phosphate (OSP) for colonoscopy has emerged as an important clinical entity. In 2004, five cases of nephrocalcinosis and irreversible renal failure after bowel preparation with OSP were reported. More recently, several retrospective studies have shown that the incidence of acute kidney injury after OSP use is in the range of 1–4%, similar to the incidence of contrast nephropathy in the general population. The degree of renal… 

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TLDR
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A 65-year-old woman admitted to the hospital with an elevated serum creatinine concentration associated with leukocyturia and erythrocyturia was diagnosed with phosphate nephropathy, most probably secondary to OSP ingestion.
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TLDR
This review focuses on the main strategies that can improve the cleansing quality with a special interest on those clinical conditions that have been associated with a poor bowel preparation quality, such as patients with chronic constipation, history of bowel resection, liver cirrhosis, diabetes mellitus and chronic kidney disease.
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TLDR
This is the first reported case of phosphate nephropathy in Australia and guidelines recommend that phosphate bowel preparation be avoided in patients with these risk factors and that for other patients the following precautions be taken: the minimal effective dose of phosphate bowel Preparation.
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