Is anti‐viral defence the evolutionary origin of mRNA turnover? (Comment on DOI 10.1002/bies.201600100)

  • Jan Rehwinkel
  • Published 2016 in
    BioEssays : news and reviews in molecular…

Abstract

In this issue of BioEssays, Hamid and Makeyev explore an interesting new idea regarding the evolutionary origins of regulated mRNA turnover pathways [1]. One such pathway is nonsensemediated decay (NMD) that detects and targets for degradation a subset of mRNAs including transcripts with premature translation termination codons. The authors develop a model… (More)
DOI: 10.1002/bies.201600140

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