Is amyloid-β harmful to the brain? Insights from human imaging studies.
@article{Jagust2016IsAH, title={Is amyloid-$\beta$ harmful to the brain? Insights from human imaging studies.}, author={William J. Jagust}, journal={Brain : a journal of neurology}, year={2016}, volume={139 Pt 1}, pages={ 23-30 } }
Although the amyloid-β protein associated with the Alzheimer's disease plaque has been detectable in living people for over a decade, its importance in the pathogenesis of Alzheimer's disease is still debated. The frequent presence of amyloid-β in the brains of cognitively healthy older people has been interpreted as evidence against a causative role. If amyloid-β is crucial to the development of Alzheimer's disease, it should be associated with other Alzheimer's disease-like neurological…
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