Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?

  title={Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?},
  author={L. Taraseviciene-Stewart and I. Douglas and P. Nana-Sinkam and J. D. Lee and R. Tuder and M. Nicolls and N. Voelkel},
  journal={Proceedings of the American Thoracic Society},
  volume={3 8},
  • L. Taraseviciene-Stewart, I. Douglas, +4 authors N. Voelkel
  • Published 2006
  • Medicine
  • Proceedings of the American Thoracic Society
  • The alveolar destruction leading to airspace enlargement in patients with end-stage chronic obstructive pulmonary disease (COPD) is frequently progressive, despite smoking cessation. Several laboratories have accumulated data demonstrating the presence of immune cells in bronchial biopsy specimens and lung tissue sections from patients with COPD. Recently, the accumulation of T and B lymphocytes, often forming follicles, in the lung parenchyma from patients with severe COPD has been reported… CONTINUE READING
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