Is aldehyde dehydrogenase inhibited by sulfur compounds? In vitro and in vivo studies.

@article{Iciek2018IsAD,
  title={Is aldehyde dehydrogenase inhibited by sulfur compounds? In vitro and in vivo studies.},
  author={Małgorzata B Iciek and Magdalena G{\'o}rny and Anna Bilska-Wilkosz and Danuta Kowalczyk-Pachel},
  journal={Acta biochimica Polonica},
  year={2018},
  volume={65 1},
  pages={
          125-132
        }
}
Aldehyde dehydrogenase (ALDH) catalyzes the critical step of ethanol metabolism, i.e. transformation of toxic acetaldehyde to acetic acid. It is a redox sensitive protein with the key Cys in its active site. Recently, it has been documented that activity of some proteins can be modified by sulfur-containing molecules called reactive sulfur species leading to the formation of hydro- persulfides. The aim of the present study was to examine whether ALDH activity can be modified in this way… CONTINUE READING
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SHOWING 1-10 OF 36 REFERENCES

S-sulfhydration as a cellular redox regulation

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