Is adalimumab in combination with methotrexate a safe and efficacious treatment for early rheumatoid arthritis?

@article{Smolen2006IsAI,
  title={Is adalimumab in combination with methotrexate a safe and efficacious treatment for early rheumatoid arthritis?},
  author={Josef S Smolen and Daniel Aletaha},
  journal={Nature Clinical Practice Rheumatology},
  year={2006},
  volume={2},
  pages={242-243}
}
BACKGROUND Rheumatoid arthritis (RA) is a chronic inflammatory disease. Damage to articular cartilage and subchondral bone is particularly severe in the early stages of the disease. Several therapeutic options, including the use of tumor-necrosis-factor (TNF) inhibitors and disease-modifying antirheumatic drugs (DMARDs), for the treatment of early RA are known to result in favourable short-term and long-term benefits. Combination treatment of anti-TNF agents with another thera peutic has not… CONTINUE READING