Is a pre-operative brain natriuretic peptide or N-terminal pro-B-type natriuretic peptide measurement an independent predictor of adverse cardiovascular outcomes within 30 days of noncardiac surgery? A systematic review and meta-analysis of observational studies.

@article{Karthikeyan2009IsAP,
  title={Is a pre-operative brain natriuretic peptide or N-terminal pro-B-type natriuretic peptide measurement an independent predictor of adverse cardiovascular outcomes within 30 days of noncardiac surgery? A systematic review and meta-analysis of observational studies.},
  author={G. Karthikeyan and Ross A. Moncur and O. Levine and D. Heels-Ansdell and M. Chan and P. Alonso-Coello and S. Yusuf and D. Sessler and J. Villar and O. Berwanger and M. McQueen and A. Mathew and S. Hill and S. Gibson and C. Berry and Huei-Ming Yeh and P. Devereaux},
  journal={Journal of the American College of Cardiology},
  year={2009},
  volume={54 17},
  pages={
          1599-606
        }
}
  • G. Karthikeyan, Ross A. Moncur, +14 authors P. Devereaux
  • Published 2009
  • Medicine
  • Journal of the American College of Cardiology
  • OBJECTIVES We conducted a systematic review and meta-analysis to determine if pre-operative brain natriuretic peptide (BNP) (i.e., BNP or N-terminal pro-B-type natriuretic peptide [NT-proBNP]) is an independent predictor of 30-day adverse cardiovascular outcomes after noncardiac surgery. BACKGROUND Pre-operative clinical cardiac risk indices have only modest predictive power. BNP predicts adverse cardiovascular outcomes in a variety of nonsurgical settings and may similarly predict these… CONTINUE READING
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