Is a myogenic response involved in deep inspiration-induced bronchoconstriction in asthmatics?

@article{Marthan1989IsAM,
  title={Is a myogenic response involved in deep inspiration-induced bronchoconstriction in asthmatics?},
  author={Roger Marthan and Ann J. Woolcock},
  journal={The American review of respiratory disease},
  year={1989},
  volume={140 5},
  pages={1354-8}
}
The mechanisms by which a deep inspiration (DI) induces bronchoconstriction in some asthmatic patients remain unclear. As a calcium-dependent myogenic response could be involved, we examined the effect of a potent voltage-dependent calcium channel (VDC) antagonist, nifedipine (20 mg administered sublingually) versus placebo, on the DI-induced change in plethysmographic specific airway conductance (SGaw) in six asthmatic patients and six healthy controls both before and after a bronchial… CONTINUE READING

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