• DOI:10.1002/hep.21099
Corpus ID: 21087010

Is a leaky gut involved in the pathogenesis of intrahepatic cholestasis of pregnancy?

@article{Reyes2006IsAL,
  title={Is a leaky gut involved in the pathogenesis of intrahepatic cholestasis of pregnancy?},
  author={H. Reyes and R. Zapata and I. Hern{\'a}ndez and M. Gotteland and L. Sandoval and M. I. Jir{\'o}n and J. Palma and R. Almuna and J. Silva},
  journal={Hepatology},
  year={2006},
  volume={43}
}

• H. Reyes, R. Zapata, +6 authors J. Silva
• Published 2006
• Medicine
• Hepatology

Increased gastrointestinal permeability has been demonstrated in several liver diseases. It may facilitate the absorption of gut‐derived endotoxin‐stimulating Kupffer cells to release proinflammatory cytokines or other potentially hepatotoxic compounds. We examined gastrointestinal permeability, plasma levels of anti‐lipopolysacharides (anti‐LPS), and four proinflammatory cytokines in 20 patients with intrahepatic cholestasis of pregnancy (ICP) compared with 22 normal pregnant and 29 non… Expand

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