Is Triclosan a neurotoxic agent?

@article{Ruszkiewicz2017IsTA,
  title={Is Triclosan a neurotoxic agent?},
  author={Joanna A Ruszkiewicz and Shaojun Li and Maliya B Rodriguez and Michael Aschner},
  journal={Journal of Toxicology and Environmental Health, Part B},
  year={2017},
  volume={20},
  pages={104 - 117}
}
ABSTRACT Triclosan (TCS) is an antibacterial agent that has been used in many products since 1960s. Given its broad usage as an antiseptic TCS is present ubiquitously in the environment. Trace levels of TCS continue to be detected in many organisms, and it has been shown to be particularly toxic to aquatic species. The mechanisms underlying TCS-mediated toxicity include hormone dyshomeostasis, induction of oxidative stress, apoptosis and inflammation. Although TCS has been considered to be non… 
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Triclosan: antimicrobial mechanisms, antibiotics interactions, clinical applications, and human health.
TLDR
The current understanding of the antimicrobial mechanisms of Triclosan is reviewed, how microbes become resistant to Tricrosan, and the synergistic and antagonistic effects of Trichlosan with different antibiotics are reviewed.
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TLDR
It is discovered that TCS substantially accelerates hepatocellular carcinoma (HCC) development, acting as a liver tumor promoter, and that the mechanism of TCS-induced mouse liver pathology may be relevant to humans.
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TLDR
Concern has been raised over TCS's potential for endocrine disruption, as the antimicrobial has been shown to disrupt thyroid hormone homeostasis and possibly the reproductive axis, and there is strong evidence that aquatic species such as algae, invertebrates and certain types of fish are much more sensitive to TCS than mammals.
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TLDR
Data is reviewed on the human exposure, environmental fate, efficacy of anti-microbial activity, absorption, distribution, metabolism and elimination, endocrine disrupting effects, and toxicity of triclosan.
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TLDR
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TLDR
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TLDR
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TLDR
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