Is TTF1 a good immunohistochemical marker to distinguish primary from metastatic lung adenocarcinomas?

@article{ReisFilho2000IsTA,
  title={Is TTF1 a good immunohistochemical marker to distinguish primary from metastatic lung adenocarcinomas?},
  author={Jorge S Reis-Filho and Carla Carrilho and Carla Valent{\'i} and Dina Raquel Aguilera Leit{\~a}o and Carlos Alberto dos Reis Ribeiro and S G Ribeiro and F Schmitt},
  journal={Pathology, research and practice},
  year={2000},
  volume={196 12},
  pages={835-40}
}
To evaluate the immunohistochemical expression of thyroid transcription factor 1 (TTF1) in primary and metastatic pulmonary adenocarcinomas, and test the diagnostic accuracy of this antibody, two surgical pathologists independently evaluated 34 cases of adenocarcinomas in the lung without clinical data and tried to distinguish between primary and metastatic cases using histological criteria exclusively. Thirteen cases were primary in the lung and 21 were metastases of extrapulmonary… CONTINUE READING

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