Is Obesity Associated with an Increased Risk for Airway Hyperresponsiveness and Development of Asthma?

@inproceedings{Sharma2008IsOA,
  title={Is Obesity Associated with an Increased Risk for Airway Hyperresponsiveness and Development of Asthma?},
  author={Sat Sharma and A. Tailor and Richard John Warrington and Mary Cheang},
  booktitle={Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology},
  year={2008}
}
We investigated the association between airway hyperresponsiveness (AHR) and obesity in adults referred for confirmation of asthma diagnosis. Data were analyzed for obesity class I (body mass index [BMI] 30-34.9 kg/m2), class II (BMI ≥ 35-39.9 kg/m2), and class III (BMI ≥ 40 kg/m2). Of 861 subjects, 401 demonstrated AHR; the mean dose of methacholine was 4.16 ± 2.55 mg/mL. A significant association between obesity and AHR was evident for all subjects: the odds ratio was 1.37 (95% CI 1.02-1.82… CONTINUE READING

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  • 2015
VIEW 1 EXCERPT
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References

Publications referenced by this paper.
SHOWING 1-10 OF 47 REFERENCES

Toward a definition of asthma for epidemiology.

  • The American review of respiratory disease
  • 1992
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Obesity and asthma.

  • American journal of respiratory and critical care medicine
  • 2006