Is NADH Effective in the Treatment of Parkinson’s Disease?

  title={Is NADH Effective in the Treatment of Parkinson’s Disease?},
  author={Russell H Swerdlow},
  journal={Drugs \& Aging},
  • R. Swerdlow
  • Published 1 October 1998
  • Biology
  • Drugs & Aging
Most Parkinson’s disease (PD) treatments palliate symptoms by increasing nigrostriatal dopaminergic tone. A unique strategy for accomplishing this pharmacological end-point proposes using reduced nicotinamide adenine dinucleotide (NADH) to boost endogenous dopamine production, since NADH indirectly supplies reducing equivalents to the rate-limiting, tyrosine hydroxylase-catalysed step of dopamine synthesis. Support for using NADH in PD treatment includes claims that NADH stimulates tyrosine… 

A synopsis on the role of tyrosine hydroxylase in Parkinson's disease.

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    Frontiers in bioscience : a journal and virtual library
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