Is KRAS Mutation Associated with Interval Colorectal Cancers?

  title={Is KRAS Mutation Associated with Interval Colorectal Cancers?},
  author={Aasma Shaukat and Mustafa A. Arain and Ruth E. Anway and Sharad Manaktala and Laurie Pohlman and Bharat Thyagarajan},
  journal={Digestive Diseases and Sciences},
Colorectal cancers diagnosed in the interval after a complete colonoscopy may occur due to rapid tumor growth. Interval colorectal cancers are associated with microsatellite instability (MSI). Our aim was to study the association of KRAS mutation with interval colorectal cancers and MSI. We searched our institution’s cancer registry for interval colorectal cancers, defined as colorectal cancers that developed within 5 years of a complete colonoscopy. These were frequency matched to patients… CONTINUE READING
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