Is Insulin Resistance a Feature of or a Primary Risk Factor for Cardiovascular Disease?

@article{Laakso2015IsIR,
  title={Is Insulin Resistance a Feature of or a Primary Risk Factor for Cardiovascular Disease?},
  author={Markku Laakso},
  journal={Current Diabetes Reports},
  year={2015},
  volume={15},
  pages={1-9}
}
The two major pathophysiological abnormalities in type 2 diabetes are insulin resistance and impaired insulin secretion. Insulin resistance is a general term meaning that insulin does not exert its normal effects in insulin-sensitive target tissues, such as skeletal muscle, adipose tissue, and liver, the major target tissues for insulin action in glucose metabolism. Insulin resistance (IR) promotes cardiovascular disease via multiple mechanisms, including changes in classic cardiovascular risk… CONTINUE READING
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