Is Indeterminate Colitis Determinable?

  title={Is Indeterminate Colitis Determinable?},
  author={William J. Tremaine},
  journal={Current Gastroenterology Reports},
  • W. Tremaine
  • Published 8 February 2012
  • Medicine
  • Current Gastroenterology Reports
About 10% of patients with colitis due to inflammatory bowel disease have indeterminate colitis. Despite newer diagnostic tools, the frequency has not diminished over the past 33 years. The current preferred term among academicians is colonic inflammatory bowel disease unclassified (IBDU), although indeterminate colitis is the term endorsed for inclusion in the ICD-10 coding system. Indeterminate colitis is more frequent among children. The anti-Saccharomyces cerevisiae (ASCA) and perinuclear… 
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What is the incidence, prevalence, and natural history of indeterminate colitis?
  • G. Meucci
  • Medicine
    Inflammatory bowel diseases
  • 2008
It is generally believed that in most cases IC merely represents a provisional diagnosis; indeed, follow-up studies have shown that a vast proportion of patients are eventually reclassified as being affected by either CD or UC, and up to 20% as not affected by IBD.
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The term IBD unclassified (IBDU) is confirmed, as suggested by the Montreal Working Party 2005 for patients with clinically chronic colitis, that clearly have IBD but when definitive features of CD or UC are absent.
The value of serologic markers in indeterminate colitis: a prospective follow-up study.
Evaluated the value of anti-Saccharomyces cerevisiae antibodies (ASCA) and perinuclear antineutrophil cytoplasmic antibodies (pANCA) to increase diagnostic accuracy in categorizing IC and results so far show that ASCA+/ pANCA- predicts CD in 80% of patients with IC and ASCA-/pANca+ predicts UC in 63.6%.
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  • D. Antonioli
  • Medicine
    Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • 2005
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Overlap in the spectrum of non-specific inflammatory bowel disease--'colitis indeterminate'.
  • A. Price
  • Medicine
    Journal of clinical pathology
  • 1978
Case of colitis indeterminate form a small distinctive group in the spectrum of inflammatory bowel disease which is characterised by a common pattern of pathology that presents a diagnostic dilemma.
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