Is Helicobacter pylori eradication required for non-steroidal anti-inflammatory drugassociated erosions and ulcers?

  title={Is Helicobacter pylori eradication required for non-steroidal anti-inflammatory drugassociated erosions and ulcers?},
  author={A.Ye. Karateyev and A. Tsurgan and Nataliya Gontarenko and Yekaterina Moroz},
1 Citations
Gastro-Intestinal Tract Complications During Antithrombotic Therapy
Most of patients who received ATA, the commonly observed erosive and ulcerous alterations in the digestive system might become a source of bleeding, as well as the elderly age, ulcer history, concomitant intake of NSAIDS, and smoking habit were associated with a higher occurrence of pathological alterations of digestive system.


Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study. Helicobacter Eradication for Lesion Prevention.
H. pylori eradication in long-term users of NSAIDs with current or previous peptic ulceration, dyspepsia, or both who continued to use NSAIDs led to impaired healing of gastric ulcers and did not affect the rate ofpeptic ulcers or dyspePSia over 6 months.
Helicobacter pylori infection in older people.
An overview of the epidemiology, diagnosis, clinical manifestations and therapy of H. pylori infection in elderly people is presented.
The regulation of gastric acid secretion – clinical perspectives
It is remarkable that the interaction between Hp and gastrin may explain the pathogenesis of most diseases in the upper gastrointestinal tract.
Should NSAID/low‐dose aspirin takers be tested routinely for H. pylori infection and treated if positive? Implications for primary risk of ulcer and ulcer relapse after initial healing
Testing for, and cure of, H. pylori infection is recommended in patients prior to the initiation of NSAID therapy and in those who are currently receiving NSAIDs and have a history of dyspepsia, peptic ulcer or ulcer complications.
Effects of Helicobacter pylori infection on long-term risk of peptic ulcer bleeding in low-dose aspirin users.
The long-term incidence of recurrent ulcer bleeding with ASA use is low after H pylori infection is eradicated, and tests for H plyori infection can be used to assign high-risk ASA users to groups that require different gastroprotective strategies.
Peptic ulcer disease.