Is Gompertzian or exponential kinetics a valid description of individual human cancer growth?

@article{Retsky1990IsGO,
  title={Is Gompertzian or exponential kinetics a valid description of individual human cancer growth?},
  author={Michael W. Retsky and Douglas E. Swartzendruber and Robert H. Wardwell and Paul D. Bame},
  journal={Medical hypotheses},
  year={1990},
  volume={33 2},
  pages={95-106}
}
It is generally accepted that human cancers grow in an exponential or Gompertzian manner. This assumption is based on analysis of the growth of transplantable animal tumors and on averages of tumor growth in human populations. A computer model of breast cancer in individual patients has raised some doubts about this assumption. The computer model predicts an irregular pattern of tumor growth that incorporates plateaus or dormant periods separated by Gompertzian growth spurts. Since growth… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…