Is EBV persistence in vivo a model for B cell homeostasis?

  title={Is EBV persistence in vivo a model for B cell homeostasis?},
  author={Ghazala H. Khan and Emily M Miyashita and Bin Yang and Gregory J. Babcock and David Thorley-Lawson},
  volume={5 2},
We have measured the absolute numbers of EBV-infected B cells in the peripheral blood of healthy persistently infected individuals. Single measurements on a panel of 15 healthy individuals demonstrate that the frequency varies over a wide range from 1-50 per 10(6) B cells. Repeat measurements over 1-3.5 years on several individuals whose frequencies varied over a 10-fold range showed that the variation does not represent the fluctuation in the frequency that can occur within an individual… CONTINUE READING

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