Is Development of High-Grade Gliomas Sulfur-Dependent?

@inproceedings{Wrbel2014IsDO,
  title={Is Development of High-Grade Gliomas Sulfur-Dependent?},
  author={Maria Wr{\'o}bel and Jerzy Czubak and Patrycja Bronowicka-Adamska and Halina Jurkowska and Dariusz Adamek and Bolesław Papla},
  booktitle={Molecules},
  year={2014}
}
We characterized γ-cystathionase, rhodanese and 3-mercaptopyruvate sulfurtransferase activities in various regions of human brain (the cortex, thalamus, hypothalamus, hippocampus, cerebellum and subcortical nuclei) and human gliomas with II to IV grade of malignancy (according to the WHO classification). The human brain regions, as compared to human liver, showed low γ-cystathionase activity. The activity of rhodanese was also much lower and it did not vary significantly between the… CONTINUE READING
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