Is BRAF mutation associated with lymph node metastasis in patients with papillary thyroid cancer?

@article{Lee2012IsBM,
  title={Is BRAF mutation associated with lymph node metastasis in patients with papillary thyroid cancer?},
  author={Kathleen C. Lee and Carol M Y Li and Eric B. Schneider and Yongchun Wang and Helina Somervell and Matthew R. Krafft and Christopher B Umbricht and Martha A. Zeiger},
  journal={Surgery},
  year={2012},
  volume={152 6},
  pages={977-83}
}
BACKGROUND Some have proposed using V600E BRAF mutation status to dictate the surgical management of patients with papillary thyroid cancer (PTC). However, well-designed studies examining BRAF association with aggressive clinicopathologic features of PTC, including the presence of lymph node metastases (LNM), in patients who have undergone routine central lymph node dissection (CLND), are lacking. METHODS Under institutional review board approval, 63 patients diagnosed with PTC on fine-needle… CONTINUE READING

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