Is Adjuvant Chemotherapy Really Needed After Curative Surgery for Rectal Cancer Patients Who are Node-Negative After Neoadjuvant Chemoradiotherapy?

@article{Kiran2011IsAC,
  title={Is Adjuvant Chemotherapy Really Needed After Curative Surgery for Rectal Cancer Patients Who are Node-Negative After Neoadjuvant Chemoradiotherapy?},
  author={Ravi P Kiran and Hasan Tarik Kirat and Adele N. Burgess and Pasha J. Nisar and Matthew F Kalady and Ian C. Lavery},
  journal={Annals of Surgical Oncology},
  year={2011},
  volume={19},
  pages={1206-1212}
}
Adjuvant chemotherapy is currently offered, as standard, after curative resection for patients with rectal cancer who receive neoadjuvant chemoradiation (NCRT). We postulate that adjuvant chemotherapy adds minimal oncologic benefit for patients who undergo total mesorectal excision who are node-negative after neoadjuvant chemoradiation. From a prospective, institutional cancer database, rectal cancer patients who completed neoadjuvant chemoradiation and curative surgery (2000–2008) and were… CONTINUE READING
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