Is APACHE II a useful tool for clinical research?

  title={Is APACHE II a useful tool for clinical research?},
  author={Rui Paulo Moreno and Antonio Paulo Nassar},
  booktitle={Revista Brasileira de terapia intensiva},
The population of patients admitted to the intensive care unit (ICU) is quite heterogeneous. Overall, the outcome of ICU treatment depends on the site, cause of admission, age, prior comorbidities, and acute physiological changes at admission and during the first several hours of treatment. Predictions of the in-hospital mortality of ICU patients play important roles with respect to inclusion/exclusion criteria in clinical trials, comparisons of observed mortality with predicted mortality using… CONTINUE READING