Is 3-dimensional echocardiographic area strain diagnostically superior to longitudinal and circumferential strain?

Abstract

(A) Circulating aldosterone levels in 3-week post-myocardial infarction (MI) rats at 7 days after in vivo adrenal-targeted, adenoviral-mediated b-arrestin1 (barr1) gene delivery and with simultaneous treatments with vehicle (control) or with: 1) 30 mg/kg body weight/day valsartan; 2) 10 mg/kg body weight/day candesartan; or 3) 40 mg/kg body weight/day irbesartan (all via drinking water). *p < 0.05 versus vehicle or irbesartan (n 1⁄4 5 rats/group). (B) Ejection fraction (EF%) and increases in cardiac contractile function (þdP/dtmax) afforded by the drug treatments in these animals at the end of the 7-day treatments (maximal dose of isoproterenol [Max. Iso]: 333 ng/kg body weight). *p < 0.05 versus vehicle; †p < 0.05 versus irbesartan (n 1⁄4 5 rats/group). Letters J A C C V O L . 6 4 , N O . 2 5 , 2 0 1 4

DOI: 10.1016/j.jacc.2014.09.063

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Cite this paper

@article{Flachskampf2014Is3E, title={Is 3-dimensional echocardiographic area strain diagnostically superior to longitudinal and circumferential strain?}, author={Frank Flachskampf}, journal={Journal of the American College of Cardiology}, year={2014}, volume={64 25}, pages={2806-7} }