Irx1 and Irx2 Are Coordinately Expressed and Regulated by Retinoic Acid, TGFβ and FGF Signaling during Chick Hindlimb Development

@inproceedings{DazHernndez2013Irx1AI,
  title={Irx1 and Irx2 Are Coordinately Expressed and Regulated by Retinoic Acid, TGFβ and FGF Signaling during Chick Hindlimb Development},
  author={Martha Elena D{\'i}az-Hern{\'a}ndez and Marcia Bustamante and Claudio Iv{\'a}n Galv{\'a}n-Hern{\'a}ndez and Jes{\'u}s Chimal-Monroy},
  booktitle={PloS one},
  year={2013}
}
The Iroquois homeobox (Irx) genes play a crucial role in the regionalization and patterning of tissues and organs during metazoan development. The Irx1 and Irx2 gene expression pattern during hindlimb development has been investigated in different species, but its regulation during hindlimb morphogenesis has not been explored yet. The aim of this study was to evaluate the gene expression pattern of Irx1 and Irx2 as well as their regulation by important regulators of hindlimb development such as… CONTINUE READING

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