Irritable bowel syndrome: a clinical review.

@article{Chey2015IrritableBS,
  title={Irritable bowel syndrome: a clinical review.},
  author={William D. Chey and Jacob E. Kurlander and S Eswaran},
  journal={JAMA},
  year={2015},
  volume={313 9},
  pages={
          949-58
        }
}
IMPORTANCE Irritable bowel syndrome (IBS) affects 7% to 21% of the general population. It is a chronic condition that can substantially reduce quality of life and work productivity. OBJECTIVES To summarize the existing evidence on epidemiology, pathophysiology, and diagnosis of IBS and to provide practical treatment recommendations for generalists and specialists according to the best available evidence. EVIDENCE REVIEW A search of Ovid (MEDLINE) and Cochrane Database of Systematic Reviews… 
Irritable bowel syndrome: the clinical approach.
TLDR
An updated overview on epidemiology, pathogenesis, diagnosis and treatment of IBS is offered, with a strong reassuring physician-patient relationship crucial.
Is irritable bowel syndrome an infectious disease?
TLDR
Clinical evidence from treatment trials with both probiotics and antibiotics shows improvement in global IBS symptoms that correlates with breath test normalization in diarrhea-predominant patients, and underlying infectious disease may provide a unifying hypothesis that better explains the overall symptomatology.
Irritable bowel syndrome – psychiatric issues
TLDR
Certain psychiatric aspects of the irritable bowel syndrome meet the criteria for a somatization disorder and further research is needed to determine the causes of comorbidity of IBS and mental disorders.
The overlap between irritable bowel syndrome and organic gastrointestinal diseases.
TLDR
This Review endeavours to aid clinicians who practise adult gastroenterology in recognising the potential overlap between IBS and organic gastrointestinal diseases and highlights areas in need of further research and clarity.
Management of Irritable Bowel Syndrome: Physician-Dietitian Collaboration.
  • C. Ireton-Jones, M. Weisberg
  • Medicine
    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
  • 2020
TLDR
Patients with IBS should meet with a qualified dietitian who can provide the complex diet information in a practicable form, asician-dietitian collaboration is invaluable for IBS patients to achieve a successful outcome.
Complementary Health Approaches for Irritable Bowel Syndrome
TLDR
There is sound evidence to support the use of such modalities to augment the care and overall quality of life of patients with IBS.
Diarrhea-Predominant Irritable Bowel Syndrome: Medical Management Update
TLDR
Key clinical trial data for the currently available pharmacological options for IBS-D in Canada are presented to provide an overview of the efficacy and safety of these agents.
Diets and Irritable Bowel Syndrome
TLDR
According to the results, the effects of some food groups on IBS are unclear, and research in this regard is limited to food patterns, and further investigations are required in order to reach conclusive results.
Targeted pharmacotherapy of irritable bowel syndrome.
TLDR
This review provides an update related to clinical trial data for novel treatment modalities in IBS targeting the gut epithelium secretagogue receptors and channels and newly approved pharmacotherapy options with proven efficacy and acceptable side-effect profiles are available.
Irritable Bowel Syndrome
TLDR
Treatment of IBS encompasses a combination of lifestyle and diet modifications, medications, and behavioral interventions, which varies on the individual and their symptoms.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 99 REFERENCES
Irritable bowel syndrome: the role of food in pathogenesis and management.
TLDR
Although many patients with IBS adopt any one of a host of dietary changes in an attempt to alleviate their symptoms, there has been, until recently little scientific basis for any dietary recommendation in IBS.
Somatic comorbidities of irritable bowel syndrome: a systematic analysis.
TLDR
The knowledge and structured assessment of comorbid somatic symptoms might allow to identify subgroups of IBS patients with special characteristics and lead to adaptation of the therapeutic concept.
An Evidence-Based Position Statement on the Management of Irritable Bowel Syndrome
TLDR
This monograph was developed to educate physicians about its epidemiology, diagnostic approach, and treatments of Irritable Bowel Syndrome to critically evaluate the rapidly expanding research about IBS.
Prevalence of Symptoms Meeting Criteria for Irritable Bowel Syndrome in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis
TLDR
Symptoms compatible with IBS were significantly higher in patients with IBD compared with non-IBD controls, even among those felt to be in remission, and IBS-type symptoms were also significantly more common in CD than in UC patients, and in those with active disease.
Mucosal inflammation as a potential etiological factor in irritable bowel syndrome: a systematic review
TLDR
Low-grade mucosal inflammation, particularly mast cell activation, may be a contributory factor in the pathogenesis of IBS and Mast cell stabilizers warrant further assessment as a potential therapy in the condition.
The Utility of Probiotics in the Treatment of Irritable Bowel Syndrome: A Systematic Review
TLDR
Bifidobacterium infantis 35624 showed significant improvement in the composite score for abdominal pain/discomfort, bloating/distention, and/or bowel movement difficulty compared with placebo in two appropriately designed studies; there is inadequate data to comment on the efficacy of other probiotics.
Prevalence of irritable bowel syndrome-type symptoms in patients with celiac disease: a meta-analysis.
  • A. Sainsbury, D. Sanders, A. Ford
  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2013
TLDR
IBS-type symptoms occur frequently in patients with CD and are more common than among controls, and adherence to a GFD might be associated with a reduction in symptoms.
Bowel Habit Subtypes and Temporal Patterns in Irritable Bowel Syndrome: Systematic Review
Irritable bowel syndrome (IBS) is a heterogeneous condition characterized by the presence of abdominal discomfort or pain and bowel habit alterations: constipation (C-IBS), diarrhea (D-IBS), or
Prevalence, characteristics, and impact of bloating symptoms in patients with irritable bowel syndrome.
TLDR
Bloating symptoms are common in patients with IBS, and their prevalence and relative severity differ on the basis of sex and IBS subtype, and they are associated with a decrease in the quality of life and increases in health care utilization and use of medications.
American College of Gastroenterology Monograph on the Management of Irritable Bowel Syndrome and Chronic Idiopathic Constipation
TLDR
The criteria developed through the Rome process, currently in its third iteration, have been those most widely employed in clinical trials and, therefore, most relevant to any review of the literature on the management of these disorders.
...
1
2
3
4
5
...