Irritability, psychomotor agitation and progressive insomnia induced by bilateral stimulation of the area surrounding the dorsal subthalamic nucleus (zona incerta) in Parkinson’s disease patients

@article{Merello2009IrritabilityPA,
  title={Irritability, psychomotor agitation and progressive insomnia induced by bilateral stimulation of the area surrounding the dorsal subthalamic nucleus (zona incerta) in Parkinson’s disease patients},
  author={Marcelo Merello and Sol Cavanagh and Santiago Perez-Lloret and Eliana Roldan and Veronica Bruno and Eduardo Tenca and Ram{\'o}n E Leiguarda},
  journal={Journal of Neurology},
  year={2009},
  volume={256},
  pages={2091-2093}
}
It has been suggested that zona incerta (ZI) stimulation can have significant positive effect on motor signs, with comparable or even better results than STN stimulation [11]. Unfortunately those reports lack cognitive and psychiatric evaluation, and no data on ZI-DBS effects of these domains, as well as on other non motor domains such as sleep, have been reported. We describe here two patients with Parkinson’s Disease (PD) suffering psychiatric complications, namely irritability, psychomotor… CONTINUE READING