• Corpus ID: 28180596

Irreversible inhibition of hepatic fatty acid salt uptake by photoaffinity labeling with 11, 11-azistearate.

@article{Schmider1996IrreversibleIO,
  title={Irreversible inhibition of hepatic fatty acid salt uptake by photoaffinity labeling with 11, 11-azistearate.},
  author={Wolfgang Schmider and Alfred Fahr and Rolf Voges and Wolfgang Gerok and Gerhart Kurz},
  journal={Journal of lipid research},
  year={1996},
  volume={37 4},
  pages={
          739-53
        }
}
In order to have a model compound for detection of proteins involved in transport and metabolism of long-chain fatty acid salts by photoaffinity labeling 11,11-azistearate and 11,11-azi[G-3H]stearate (specific radioactivity 2.78 TBq/mmol) were synthesized. The suitability of 11,11-azi[G-3H]stearate for photoaffinity labeling was demonstrated by incorporation into BSA (bovine serum albumin) and H-FABP (hepatic fatty acid salt-binding protein) of rat liver. Repeated photoaffinity labeling… 

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