Irreversible electroporation facilitates gene transfer of a GM-CSF plasmid with a local and systemic response.


BACKGROUND Electroporation uses an electric field to induce pores in the cell membrane that can transfer macromolecules into target cells. Modulation of electrical parameters leads to irreversible electroporation (IRE), which is being developed for tissue ablation. We sought to evaluate whether the application of IRE may induce a lesser electric field in… (More)
DOI: 10.1016/j.surg.2013.06.005

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