Irregularities and power law distributions in the breathing pattern in preterm and term infants.
@article{Frey1998IrregularitiesAP,
title={Irregularities and power law distributions in the breathing pattern in preterm and term infants.},
author={Urs Frey and Michael Silverman and A L Barabasi and B{\'e}la Suki},
journal={Journal of applied physiology},
year={1998},
volume={85 3},
pages={
789-97
}
}Unlike older children, young infants are prone to develop unstable respiratory patterns, suggesting important differences in their control of breathing. We examined the irregular breathing pattern in infants by measuring the time interval between breaths ("interbreath interval"; IBI) assessed from abdominal movement during 2 h of sleep in 25 preterm infants at a postconceptional age of 40.5 +/- 5.2 (SD) wk and in 14 term healthy infants at a postnatal age of 8.2 +/- 4 wk. In 10 infants we…
Figures, Tables, and Topics from this paper
93 Citations
Stochastic modeling of central apnea events in preterm infants.
- MedicinePhysiological measurement
- 2016
This paradigm-stochastic modeling of cardiorespiratory control in neonatal infants to estimate risk for severe clinical events-may be a first step toward personalized risk assessment for life threatening apnea events after NICU discharge.
Point Process Modeling of Interbreath Interval: A New Approach for the Assessment of Instability of Breathing in Neonates
- Computer ScienceIEEE Transactions on Biomedical Engineering
- 2013
The results validate a new class of algorithms, based on the point process theory, for defining instantaneous measures of breathing irregularity in neonates and tested the utility of the paradigm for depicting the respiratory dynamics in neonatal rats and in preterm infants.
A point process model of respiratory dynamics in early physiological development
- Mathematics2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society
- 2011
A point process model of IBI with a lognormal parametric structure is proposed to appropriately represent the stochastic nature of the IBI distribution and provide a time-varying measure of irregularity in breathing.
Stabilizing immature breathing patterns of preterm infants using stochastic mechanosensory stimulation.
- MedicineJournal of applied physiology
- 2009
It is suggested that nonlinear properties of the immature respiratory control system can be harnessed using afferent stimuli to stabilize eupneic breathing, thereby potentially reducing the incidence of apnea and hypoxia.
Variability of Tidal Breathing Parameters in Preterm Infants and Associations with Respiratory Morbidity during Infancy: A Cohort Study
- MedicineThe Journal of pediatrics
- 2019
Lung resistance and elastance in spontaneously breathing preterm infants: effects of breathing pattern and demographics.
- MedicineJournal of applied physiology
- 2000
It is concluded that accounting for the effects of breathing pattern variability and demographic parameters on estimates of RL and EL is essential if they are to be of clinical value.
Prediction of intraventricular haemorrhage in preterm infants using time series analysis of blood pressure and respiratory signals
- MedicineScientific reports
- 2017
This approach may be useful in predictive monitoring to identify infants at high risk of developing IVH, offering caregivers more time to adjust intensive care treatment.
Analysis of the harmonic content of the tidal flow waveforms in infants.
- MedicineJournal of applied physiology
- 2001
Lower values of s and higher values of k(d) indicate an increased complexity of the feedback mechanisms determining tidal flow waveform and may be associated with disease.
Variability of End-Expiratory Lung Volume in Premature Infants
- MedicineNeonatology
- 2010
In premature infants, EelV variability pattern is modified by respiratory distress with a prolonged ‘EELV memory’, which suggests a greater instability of the control of EELV.
Fractal characteristics of breath to breath timing in sleeping infants
- MedicineRespiratory Physiology & Neurobiology
- 2004
References
SHOWING 1-10 OF 35 REFERENCES
Fractal properties in fetal breathing dynamics.
- PhysicsThe American journal of physiology
- 1992
The inverse power-law relationship in the distribution of the IBIs, together with the 1/f beta power spectra, indicate scale invariance and suggest that fractal mechanisms are involved in the regulation of fetal breathing.
Apen, translent episodes of bradycardia, and periodic breathing in preterm infants
- MedicineAmerican journal of diseases of children
- 1990
The results do not support the opinion that brief periods of apnea are abnormal when accompanied by a TEB, and the frequency with which these patterns are seen in healthy premature infants strongly suggests that they are normal findings.
Apnea of prematurity: I. Lung function and regulation of breathing.
- MedicinePediatrics
- 1984
The results indicate a decreased respiratory center output and a depressed ventilatory response to CO2 in infants with apnea, which supports the hypothesis that a central disturbance in regulation of breathing is the cause of apnea in these infants.
Clinical apnea and brain-stem neural function in preterm infants.
- MedicineThe New England journal of medicine
- 1983
The results suggest that the occurrence of apnea in preterm infants is correlated with neural function in the brain stem, and short brain-stem conduction times were observed in some infants who had prenatal stress, such as intrauterine growth retardation or maternal hypertension.
Changes in the contribution of the rib cage to tidal breathing during infancy.
- MedicineThe American review of respiratory disease
- 1990
It is concluded that by 1 yr of age, the RC contribution to tidal breathing during quiet sleep is similar to that of the adolescent, suggesting that major developmental changes in RC shape, compliance, and deformability take place during infancy.
Development of sleep-wake patterns and non-rapid eye movement sleep stages during the first six months of life in normal infants.
- Psychology, BiologyPediatrics
- 1982
The decreasing proportion of REM sleep, particularly in its daytime distribution, suggests a reciprocal relationship to the developing of wakefulness.
Correlation in stimulated respiratory neural noise.
- BiologyChaos
- 1995
It is concluded that in the presence of added ACh of concentration 250 to 500 &mgr;M, noise which occurs in spontaneous respiratory-related neural activity in the isolated brainstem-spinal cord preparation observed at uniform time intervals exhibits positive correlation.
Avalanches and power-law behaviour in lung inflation
- BiologyNature
- 1994
A model of the inflation process in which 'avalanches' of airway openings are seen is developed—with power-law distributions of both the size of avalanches and the time intervals between them—which agree quantitatively with those seen experimentally, and are reminiscent of the power- law behaviour observed for self-organized critical systems.
Paradoxical inward rib cage motion during rapid eye movement sleep in infants and young children.
- Medicine, BiologyJournal of developmental physiology
- 1987
It is found that duration of paradoxical inward rib cage motion during rapid eye movement sleep decreased significantly with age which may be explained by the changes in chest wall compliance and geometry of the rib cage occurring with growth.









