Irradiation induced expression of CD31, ICAM-1 and VCAM-1 in human microvascular endothelial cells.

@article{Quarmby2000IrradiationIE,
  title={Irradiation induced expression of CD31, ICAM-1 and VCAM-1 in human microvascular endothelial cells.},
  author={Steven Quarmby and R. Douglas Hunter and Shant Kumar},
  journal={Anticancer research},
  year={2000},
  volume={20 5B},
  pages={3375-81}
}
The adherence and migration of leukocytes through the endothelium of blood vessels is an important early event which occurs in normal tissues following ionizing irradiation but the underlying mechanisms are not fully understood. ICAM-1, VCAM-1 and CD31 are membrane proteins of endothelial cells, mediate this process when the vasculature is exposed to other inflammatory stimuli. In this study, expression of ICAM-1, VCAM-1 and CD31 on human dermal microvascular endothelial cells (HDMECs) at 72… CONTINUE READING