Irradiation-Induced Deinococcus radiodurans Genome Fragmentation Triggers Transposition of a Single Resident Insertion Sequence

@inproceedings{Pasternak2010IrradiationInducedDR,
  title={Irradiation-Induced Deinococcus radiodurans Genome Fragmentation Triggers Transposition of a Single Resident Insertion Sequence},
  author={C{\'e}cile Pasternak and Bao Ton-Hoang and Genevi{\`e}ve Coste and Adriana Bailone and Michael Chandler and Suzanne Sommer},
  booktitle={PLoS genetics},
  year={2010}
}
Stress-induced transposition is an attractive notion since it is potentially important in creating diversity to facilitate adaptation of the host to severe environmental conditions. One common major stress is radiation-induced DNA damage. Deinococcus radiodurans has an exceptional ability to withstand the lethal effects of DNA-damaging agents (ionizing radiation, UV light, and desiccation). High radiation levels result in genome fragmentation and reassembly in a process which generates… CONTINUE READING

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